Microtubule-associated serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the MAST2 gene.[5] The protein encoded by this gene controls TRAF6 and NF-kappaB activity.[6]

MAST2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMAST2, MAST205, MTSSK, microtubule associated serine/threonine kinase 2
External IDsOMIM: 612257; MGI: 894676; HomoloGene: 7428; GeneCards: MAST2; OMA:MAST2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015112
NM_001319245
NM_001324320
NM_001324321

NM_001042743
NM_008641
NM_001369061
NM_001369062

RefSeq (protein)

NP_001306174
NP_001311249
NP_001311250
NP_055927

NP_001036208
NP_032667
NP_001355990
NP_001355991

Location (UCSC)Chr 1: 45.79 – 46.04 MbChr 4: 116.31 – 116.46 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

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MAST2 has been shown to interact with PCLKC.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000086015Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000003810Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: MAST2 microtubule associated serine/threonine kinase 2".
  6. ^ Xiong H, Li H, Chen Y, Zhao J, Unkeless JC (2004). "Interaction of TRAF6 with MAST205 regulates NF-kappaB activation and MAST205 stability". J. Biol. Chem. 279 (42): 43675–83. doi:10.1074/jbc.M404328200. PMID 15308666.
  7. ^ Okazaki N, Takahashi N, Kojima S, Masuho Y, Koga H (July 2002). "Protocadherin LKC, a new candidate for a tumor suppressor of colon and liver cancers, its association with contact inhibition of cell proliferation". Carcinogenesis. 23 (7): 1139–48. doi:10.1093/carcin/23.7.1139. PMID 12117771.

Further reading

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