MAL-like protein is a protein that in humans is encoded by the MALL gene.[5][6]

MALL
Identifiers
AliasesMALL, BENE, mal, T-cell differentiation protein like, mal, T cell differentiation protein like
External IDsOMIM: 602022 MGI: 2385152 HomoloGene: 3965 GeneCards: MALL
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005434
NM_001371559
NM_001371560

NM_145532

RefSeq (protein)

NP_005425
NP_001358488
NP_001358489

NP_663507

Location (UCSC)Chr 2: 110.08 – 110.12 MbChr 2: 127.55 – 127.57 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes an element of the machinery for raft-mediated trafficking in endothelial cells. The encoded protein, a member of the MAL proteolipid family, predominantly localizes in glycolipid- and cholesterol-enriched membrane (GEM) rafts. It interacts with caveolin-1.[6]

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000144063 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027377 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Hildebrandt F, Otto E, Rensing C, Nothwang HG, Vollmer M, Adolphs J, Hanusch H, Brandis M (Nov 1997). "A novel gene encoding an SH3 domain protein is mutated in nephronophthisis type 1". Nat Genet. 17 (2): 149–53. doi:10.1038/ng1097-149. PMID 9326933. S2CID 38035697.
  6. ^ a b "Entrez Gene: MALL mal, T-cell differentiation protein-like".

Further reading edit