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Ljiljana Paša-Tolić is a Croatian research scientist who is a research fellow in Functional and Systems Biology at the Pacific Northwest National Laboratory. She is responsible for developing capability in mass spectrometry at the PNNL Environmental Molecular Sciences Laboratory. Her research looks to develop analytical techniques to modify protein abundance.[1][2]
Ljiljana Paša-Tolić | |
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| Alma mater | University of Zagreb |
| Scientific career | |
| Fields | Mass spectrometry Proteomics Metabolomics[1] |
| Institutions | Pacific Northwest National Laboratory National High Magnetic Field Laboratory |
| Thesis | (1992) |
| Website | www |
Early life and education edit
Paša-Tolić studied chemistry at the University of Zagreb.[3] She remained in Zagreb for graduate research, specializing in physical organic chemistry.[citation needed]
Research and career edit
She moved to the National High Magnetic Field Laboratory as a visiting researcher, where she developed a fourier-transform ion cyclotron resonance spectrometer to study biopolymers. She moved to the PNNL as a postdoctoral fellow in 1995.[3] Paša-Tolić is an expert in mass spectrometry and the development of analytical methods to understand molecular processes. She developed sophisticated modalities of mass spectrometry to investigate the polymerases found in plants. Her research showed that the polymerases found in Arabidopsis are actually derivatives of a polymerase found in eukaryotes.[4]
Paša-Tolić was included in the 2021 Analytical Sciences Power List.[5]
Selected publications edit
Her publications[1][2] include:
- Susan M Varnum; Daniel N Streblow; Matthew E Monroe; et al. (1 October 2004). "Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome". Journal of Virology. 78 (20): 10960–10966. doi:10.1128/JVI.78.20.10960-10966.2004. ISSN 0022-538X. PMC 521840. PMID 15452216. Wikidata Q37568012.
- Richard D. Smith; Gordon A. Anderson; Mary S. Lipton; Ljiljana Pasa-Tolic; Yufeng Shen; Thomas P. Conrads; Timothy D. Veenstra; Harold R. Udseth (May 2002). "An accurate mass tag strategy for quantitative and high-throughput proteome measurements". Proteomics. 2 (5): 513–523. doi:10.1002/1615-9861(200205)2:5<513::AID-PROT513>3.0.CO;2-W. ISSN 1615-9853. PMID 11987125. Wikidata Q58069136.
- Mary S Lipton; Ljiljana Pasa-Tolic'; Gordon A Anderson; et al. (20 August 2002). "Global analysis of the Deinococcus radiodurans proteome by using accurate mass tags". Proceedings of the National Academy of Sciences of the United States of America. 99 (17): 11049–54. Bibcode:2002PNAS...9911049L. doi:10.1073/PNAS.172170199. ISSN 0027-8424. PMC 129300. PMID 12177431. Wikidata Q24535537.
References edit
- ^ a b c Ljiljana Paša-Tolić publications indexed by Google Scholar
- ^ a b Ljiljana Paša-Tolić publications from Europe PubMed Central
- ^ a b "Staff information Ljiljana Pasa Toli".
- ^ Lutz, Diana (6 January 2009). "Plant polymerases IV and V are special forms of Polymerase II - The Source - Washington University in St. Louis". The Source. Retrieved 16 March 2023.
- ^ "Ljiljana Paša-Tolic". The Analytical Scientist. Retrieved 16 March 2023.