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Liebermeister's rule concerns the increment ratio between an adult individual's cardiac frequency and temperature when in fever. Each Celsius grade of body temperature increment corresponds to an 8 beats per minute increase in cardiac frequency.[1][2] An exception to this rule by creating a relative bradycardia is known as Faget sign (pulse-temperature dissociation) common in some diseases, especially yellow fever, tularaemia and salmonella typhi.

It is named for Carl von Liebermeister.


  1. ^ "Liebermeister's rule". Retrieved 2009-09-02.
  2. ^ "mondofacto dictionary - definition of Liebermeister's rule". 2000-03-05. Retrieved 2009-09-02.