Iron—cytochrome-c reductase

(Redirected from Iron-cytochrome-c reductase)

In enzymology, an iron—cytochrome-c reductase (created 1972 as EC 1.9.99.1, transferred 2014 to EC 1.9.98.1) is an enzyme that catalyzes the chemical reaction

iron—cytochrome-c reductase
Identifiers
EC no.1.9.98.1
CAS no.37256-52-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins
ferrocytochrome c + Fe3+ ferricytochrome c + Fe2+

Thus, the two substrates of this enzyme are ferrocytochrome c and Fe3+, whereas its two products are ferricytochrome c and Fe2+.

Classification

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This enzyme belongs to the family of oxidoreductases, specifically those acting on a heme group of donors with other acceptors.

Nomenclature

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The systematic name of this enzyme class is ferrocytochrome-c:Fe3+ oxidoreductase. This enzyme is also called iron-cytochrome c reductase.

Structure and function

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This enzyme is part of the electron transport system of Ferrobacillus ferrooxidans. It employs one cofactor, iron.

References

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  • Yates MG, Nason A (1966). "Electron transport systems of the chemoautotroph Ferrobacillus ferrooxidans. II. Purification and properties of a heat-labile iron-cytochrome c reductase". J. Biol. Chem. 241 (21): 4872–80. PMID 4288725.