Inositol 3-alpha-galactosyltransferase

In enzymology, an inositol 3-alpha-galactosyltransferase (EC 2.4.1.123) is an enzyme that catalyzes the chemical reaction

inositol 3-alpha-galactosyltransferase
Identifiers
EC no.2.4.1.123
CAS no.79955-89-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
UDP-galactose + myo-inositol UDP + O-alpha-D-galactosyl-(1->3)-1D-myo-inositol

Thus, the two substrates of this enzyme are UDP-galactose and myo-inositol, whereas its two products are UDP and [[O-alpha-D-galactosyl-(1->3)-1D-myo-inositol]].

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:myo-inositol 3-alpha-D-galactosyltransferase. Other names in common use include UDP-D-galactose:inositol galactosyltransferase, UDP-galactose:myo-inositol 1-alpha-D-galactosyltransferase, UDPgalactose:myo-inositol 1-alpha-D-galactosyltransferase, galactinol synthase, inositol 1-alpha-galactosyltransferase, and uridine diphosphogalactose-inositol galactosyltransferase. This enzyme participates in galactose metabolism.

References

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  • Pharr DM, Sox, HN, Locy RD, Huber SC (1981). "Partial characterization of the galactinol forming enzyme from leaves of Cucumis sativus L". Plant Sci. Lett. 23: 25–33. doi:10.1016/0304-4211(81)90021-3.