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Integral membrane protein 2B (ITM2B or BRI2) is a protein that in humans is encoded by the ITM2B gene.[5][6]

ITM2B
Identifiers
AliasesITM2B, ABRI, BRI, BRI2, BRICD2B, E25B, E3-16, FBD, imBRI2, RDGCA, integral membrane protein 2B
External IDsMGI: 1309517 HomoloGene: 7388 GeneCards: ITM2B
Gene location (Human)
Chromosome 13 (human)
Chr.Chromosome 13 (human)[1]
Chromosome 13 (human)
Genomic location for ITM2B
Genomic location for ITM2B
Band13q14.2Start48,232,612 bp[1]
End48,270,357 bp[1]
RNA expression pattern
PBB GE ITM2B 217731 s at fs.png

PBB GE ITM2B 217732 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_021999

NM_008410

RefSeq (protein)

NP_068839

NP_032436

Location (UCSC)Chr 13: 48.23 – 48.27 MbChr 14: 73.36 – 73.39 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

ITM2B or BRI2 is a gene located on chromosome 13. The gene is connected to familial Danish dementia and familial British dementia causing amyloid and pre-filbrillar effects similar to those seen in Alzheimer's.

ReferencesEdit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000136156 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022108 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Pittois K, Deleersnijder W, Merregaert J (Nov 1998). "cDNA sequence analysis, chromosomal assignment and expression pattern of the gene coding for integral membrane protein 2B". Gene. 217 (1–2): 141–9. doi:10.1016/S0378-1119(98)00354-0. PMID 9795190.
  6. ^ "Entrez Gene: ITM2B integral membrane protein 2B".

Further readingEdit