Inositol polyphosphate-5-phosphatase F is a protein that in humans is encoded by the INPP5F gene.[5]

INPP5F
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesINPP5F, MSTPO47, SAC2, hSAC2, MSTP007, inositol polyphosphate-5-phosphatase F
External IDsOMIM: 609389; MGI: 2141867; HomoloGene: 8962; GeneCards: INPP5F; OMA:INPP5F - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001243194
NM_001243195
NM_014937

NM_178641
NM_001346517

RefSeq (protein)

NP_001230123
NP_001230124
NP_055752

NP_001333446
NP_848756

Location (UCSC)Chr 10: 119.73 – 119.83 MbChr 7: 128.61 – 128.7 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000198825Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042105Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Inositol polyphosphate-5-phosphatase F". Retrieved 2018-05-14.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.