Inhibitor of growth protein 2 is a protein that in humans is encoded by the ING2 gene.[5][6]

ING2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesING2, ING1L, p33inhibitor of growth family member 2
External IDsOMIM: 604215; MGI: 1916510; HomoloGene: 20388; GeneCards: ING2; OMA:ING2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001291959
NM_001564

NM_023503

RefSeq (protein)

NP_001278888
NP_001555

NP_075992

Location (UCSC)Chr 4: 183.51 – 183.51 MbChr 8: 48.12 – 48.13 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000168556Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000063049Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Shimada Y, Saito A, Suzuki M, Takahashi E, Horie M (Mar 1999). "Cloning of a novel gene (ING1L) homologous to ING1, a candidate tumor suppressor". Cytogenetics and Cell Genetics. 83 (3–4): 232–5. doi:10.1159/000015188. PMID 10072587. S2CID 7081905.
  6. ^ a b "Entrez Gene: ING2 inhibitor of growth family, member 2".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.