Hydroxybutyrate-dimer hydrolase

In enzymology, a hydroxybutyrate-dimer hydrolase (EC 3.1.1.22) is an enzyme that catalyzes the chemical reaction

hydroxybutyrate-dimer hydrolase
Identifiers
EC number3.1.1.22
CAS number37278-37-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
(R)-3-((R)-3-hydroxybutanoyloxy)butanoate + H2O 2 (R)-3-hydroxybutanoate

Thus, the two substrates of this enzyme are (R)-3-((R)-3-hydroxybutanoyloxy)butanoate and H2O, whereas its product is (R)-3-hydroxybutanoate.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is (R)-3-((R)-3-hydroxybutanoyloxy)butanoate hydroxybutanoylhydrolase. This enzyme is also called D-(−)-3-hydroxybutyrate-dimer hydrolase. This enzyme participates in butanoate metabolism.

ReferencesEdit

  • Delafield FP, Cooksey KE, Doudoroff M (1965). "beta-Hydroxybutyric dehydrogenase and dimer hydrolase of Pseudomonas lemoignei". J. Biol. Chem. 240 (10): 4023–8. PMID 4954074.