Histone H1x is a protein that in humans is encoded by the H1FX gene.[5][6][7]

H1-10
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesH1-10, H1X, H1.10, H1 histone family member X, H1FX, H1.10 linker histone
External IDsOMIM: 602785; MGI: 2685307; HomoloGene: 4397; GeneCards: H1-10; OMA:H1-10 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006026

NM_198622

RefSeq (protein)

NP_006017

NP_941024

Location (UCSC)Chr 3: 129.31 – 129.32 MbChr 6: 87.96 – 87.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H1 family.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000184897Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000044927Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Yamamoto T, Horikoshi M (Dec 1996). "Cloning of the cDNA encoding a novel subtype of histone H1". Gene. 173 (2): 281–285. doi:10.1016/0378-1119(96)00020-0. PMID 8964515.
  6. ^ Albig W, Doenecke D (Feb 1998). "The human histone gene cluster at the D6S105 locus". Hum Genet. 101 (3): 284–294. doi:10.1007/s004390050630. PMID 9439656. S2CID 38539096.
  7. ^ a b "Entrez Gene: H1FX H1 histone family, member X".

Further reading

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  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Histone H1x