Glutamate dehydrogenase (NADP+)

Glutamate dehydrogenase (NADP+) (EC 1.4.1.4, glutamic dehydrogenase, dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate)), glutamic acid dehydrogenase, L-glutamate dehydrogenase, L-glutamic acid dehydrogenase, NAD(P)+-glutamate dehydrogenase, NAD(P)H-dependent glutamate dehydrogenase, glutamate dehydrogenase (NADP+)) is an enzyme with systematic name L-glutamate:NADP+ oxidoreductase (deaminating).[1][2][3][4] This enzyme catalyses the following chemical reaction

Glutamate dehydrogenase (NADP+)
Identifiers
EC no.1.4.1.4
CAS no.2604121
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
L-glutamate + H2O + NADP+ 2-oxoglutarate + NH3 + NADPH + H+

References

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  1. ^ Coulton JW, Kapoor M (April 1973). "Purification and some properties of the glutamate dehydrogenase of Salmonella typhimurium". Canadian Journal of Microbiology. 19 (4): 427–38. doi:10.1139/m73-071. PMID 4144743.
  2. ^ Grisolia S, Quijada CL, Fernandez M (1964). "Glutamate dehydrogenase from yeast and from animal tissues". Biochim. Biophys. Acta. 81: 61–70. doi:10.1016/0926-6569(64)90335-9.
  3. ^ Shiio I, Ozaki H (November 1970). "Regulation of nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase from Brevibacterium flavum, a glutamate-producing bacterium". Journal of Biochemistry. 68 (5): 633–47. PMID 4394939.
  4. ^ Smith, E.L.; Austen, B.M.; Blumenthal, K.M.; Nyc, J.F. (1975). "Glutamate dehydrogenases". In Boyer, P.D. (ed.). The Enzymes. Vol. 11 (3rd ed.). New York: Academic Press. pp. 293–367.
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