Fumigaclavine B O-acetyltransferase

Fumigaclavine B O-acetyltransferase (EC 2.3.1.205, FgaAT) is an enzyme with systematic name acetyl-CoA:fumigaclavine B O-acetyltransferase.[1] This enzyme catalyses the following chemical reaction

Fumigaclavine B O-acetyltransferase
Identifiers
EC no.2.3.1.205
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins
acetyl-CoA + fumigaclavine B CoA + fumigaclavine A

The enzyme participates in the biosynthesis of fumigaclavine C, an ergot alkaloid.

References

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  1. ^ Liu X, Wang L, Steffan N, Yin WB, Li SM (September 2009). "Ergot alkaloid biosynthesis in Aspergillus fumigatus: FgaAT catalyses the acetylation of fumigaclavine B". ChemBioChem. 10 (14): 2325–8. doi:10.1002/cbic.200900395. PMID 19672909.
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