Fructose-6-phosphate phosphoketolase

The enzyme fructose-6-phosphate phosphoketolase (EC 4.1.2.22) catalyzes the chemical reaction

fructose-6-phosphate phosphoketolase
Identifiers
EC no.4.1.2.22
CAS no.37290-57-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins
D-fructose 6-phosphate + phosphate acetyl phosphate + D-erythrose 4-phosphate + H2O

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (adding phosphate; acetyl-phosphate-forming). Other names in common use include D-fructose-6-phosphate D-erythrose-4-phosphate-lyase, and (phosphate-acetylating). This enzyme participates in pentose phosphate pathway.

References

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  • Schramm M, Klybas V, Racker E (1958). "Phospholytic cleavage of fructose-6-phosphate by fructose-6-phosphate phosphoketolase from Acetobacter xylinum". J. Biol. Chem. 233: 1283–1288.