Francisco J. Blanco García

Francisco Javier Blanco García, (1963, Honorary son of Cee, A Coruña) is a Spanish medical professional who has established a notable career in the field of rheumatology[1]. He holds the position of full professor in the Department of Physiotherapy, Medicine, and Biomedical Sciences at the Universidad de A Coruña[2]. Additionally, he serves as the Head of the Clinical and Translational Rheumatology Section at the A Coruña University Hospital and is the Coordinator of the Rheumatology-Health Research Group (GIR) at INIBIC and CICA-UDC[3]. Francisco J Blanco is also a Corresponding Academic of the Royal National Academy of Medicine of Spain[4], the Royal National Academy of Pharmacy of Spain[5], and the Royal Academy of Medicine and Surgery of Galicia[6]. Recently, he was appointed Director of the Cathedra San Rafael Foundation-UDC[7].

Education edit

Francisco Javier Blanco García began his higher education at the Universidad de Santiago de Compostela, Spain, where he graduated with a Bachelor of Science degree in Medicine and Surgery in 1987. Blanco's postgraduate journey included a residency in Rheumatology at the Hospital Universitario 12 Octubre in Madrid, completed in 1992, and a Research Fellowship in Medicine at the University of California, San Diego, Martin Lotz’s Lab in 1993-94. He achieved his PhD in Medicine from the Universidad de A Coruña, Spain, in 1998.

Research edit

Prof. Francisco Javier Blanco García's research is mainly focused on rheumatology, particularly in understanding osteoarthritis[8]. He was the first to identify apoptosis in human joint chondrocytes[9][10], linking it to cartilage destruction in osteoarthritis and associating it with nitric oxide synthesis[11][12]. Blanco's research focused on studying mitochondria's role in osteoarthritis ,leading the international study of mitochondrial genetics as biomarkers for the diagnosis, incidence, and prognosis of knee osteoarthritis[13][14][15].

He has contributed significantly to the field of protein biomarkers in osteoarthritis[16], recognized by OARSI in 2017. Blanco has also been involved in projects related to cell therapy, such as being part of the group of experts from the Spanish Ministry of Health that launched the supervised use of autologous chondrocyte implantation in Spain. He led the project to validate cellular therapy in clinical practice[17].

Dr. Blanco is a co-founder of the PROCOAC cohort (Prospective Cohort of OsteoArthritis from Coruña) created in 2006[18].

Awards edit

  • Extraordinary Award from the University of A Coruña in 1998 for his doctoral thesis titled 'In vitro study of the Effect of Nitric Oxide on Human Articular Chondrocytes: Proliferation, viability and aging".
  • Young Researcher Award in 2001 by the Government of Galicia, Santiago Compostela, Spain.
  • Premio Fundacion Barrie de la Maza by the Royal Academy of Medicine of Galicia three times (in 2003, 2006, and 2017). A Coruña, Spain.
  • Basic Science Award by the Osteoarthritis Research Society International (OARSI), Las Vegas, USA, 2017.

References edit

  1. ^ "ORCID - Francisco Javier Blanco García's profile". Retrieved 26 April 2024.
  2. ^ "University of A Coruña - Francisco Javier Blanco García's profile". Retrieved 23 April 2024.
  3. ^ "Francisco Blanco García - Servicio Gallego de Salud". portalcientifico.sergas.es. Retrieved 2024-05-02.
  4. ^ "Ilmo. Sr. D. Francisco Javier Blanco García - Real Academia Nacional de Medicina". www.ranm.es. Retrieved 2024-05-03.
  5. ^ "Académicos Correspondientes Actuales – Página 2 – Real Academia Nacional de Farmacia". ranf.com. Retrieved 2024-05-03.
  6. ^ Galegas, Páxinas. "Académicos colegiados en Galicia". www.ramycga.org (in Spanish). Retrieved 2024-05-03.
  7. ^ "Cátedra". Fundación San Rafael (in Spanish). Retrieved 2024-05-03.
  8. ^ "Francisco J Blanco's Bibliography - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2024-05-02.
  9. ^ Blanco, F. J.; Guitian, R.; Vázquez-Martul, E.; de Toro, F. J.; Galdo, F. (1998). "Osteoarthritis chondrocytes die by apoptosis. A possible pathway for osteoarthritis pathology". Arthritis and Rheumatism. 41 (2): 284–289. doi:10.1002/1529-0131(199802)41:2<284::AID-ART12>3.0.CO;2-T. ISSN 0004-3591. PMID 9485086.
  10. ^ Kim, H. A.; Blanco, F. J. (2007). "Cell death and apoptosis in osteoarthritic cartilage". Current Drug Targets. 8 (2): 333–345. doi:10.2174/138945007779940025. ISSN 1873-5592. PMID 17305511.
  11. ^ Blanco, F. J.; Ochs, R. L.; Schwarz, H.; Lotz, M. (1995). "Chondrocyte apoptosis induced by nitric oxide". The American Journal of Pathology. 146 (1): 75–85. ISSN 0002-9440. PMC 1870754. PMID 7856740.
  12. ^ De Andrés, María C.; Maneiro, Emilia; Martín, Miguel A.; Arenas, Joaquín; Blanco, Francisco J. (2013-09-11). "Nitric oxide compounds have different effects profiles on human articular chondrocyte metabolism". Arthritis Research & Therapy. 15 (5): R115. doi:10.1186/ar4295. ISSN 1478-6354. PMC 3978712. PMID 24025112.
  13. ^ Blanco, Francisco J.; López-Armada, Maria J.; Maneiro, Emilia (2004). "Mitochondrial dysfunction in osteoarthritis". Mitochondrion. 4 (5–6): 715–728. doi:10.1016/j.mito.2004.07.022. ISSN 1567-7249. PMID 16120427.
  14. ^ Blanco, Francisco J.; Rego, Ignacio; Ruiz-Romero, Cristina (2011). "The role of mitochondria in osteoarthritis". Nature Reviews. Rheumatology. 7 (3): 161–169. doi:10.1038/nrrheum.2010.213. ISSN 1759-4804. PMID 21200395.
  15. ^ Blanco, Francisco J.; Valdes, Ana M.; Rego-Pérez, Ignacio (2018). "Mitochondrial DNA variation and the pathogenesis of osteoarthritis phenotypes". Nature Reviews. Rheumatology. 14 (6): 327–340. doi:10.1038/s41584-018-0001-0. ISSN 1759-4804. PMID 29670212.
  16. ^ Ruiz-Romero, C.; López-Armada, M. J.; Blanco, F. J. (2006). "Mitochondrial proteomic characterization of human normal articular chondrocytes". Osteoarthritis and Cartilage. 14 (6): 507–518. doi:10.1016/j.joca.2005.12.004. ISSN 1063-4584. PMID 16520066.
  17. ^ Pérez-Cachafeiro, Santiago; Ruano-Raviña, Alberto; Couceiro-Follente, José; Benedí-Alcaine, Jose A.; Nebot-Sanchis, Ignacio; Casquete-Román, Ciriaco; Bello-Prats, Santiago; Couceiro-Sánchez, Gonzalo; Blanco, Francisco J (2010). "Spanish experience in autologous chondrocyte implantation". Open Orthop J. 15 (4): 14–21. doi:10.2174/1874325001004010014. PMID 20148094.
  18. ^ Oreiro-Villar, Natividad; Raga, Ana C.; Rego-Pérez, Ignacio; Pértega, Sonia; Silva-Diaz, Maite; Freire, Mercedes; Fernández-López, Carlos; Blanco, Francisco J. (2022). "PROCOAC (PROspective COhort of A Coruña) description: Spanish prospective cohort to study osteoarthritis". Reumatologia Clinica. 18 (2): 100–104. doi:10.1016/j.reumae.2020.08.004. hdl:2183/31042. ISSN 2173-5743. PMID 35153032.