Farnesyl diphosphatase (EC 3.1.7.6, FPP phosphatase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphohydrolase.[1][2] It catalyses the reaction
| Farnesyl diphosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.7.6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (2E,6E)-farnesyl diphosphate + H2O (2E,6E)-farnesol + diphosphate
The enzyme is involved in the biosynthesis of acyclic sesquiterpenoids.
References
edit- ^ Song L (February 2006). "A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol". Applied Biochemistry and Biotechnology. 128 (2): 149–58. doi:10.1385/abab:128:2:149. PMID 16484724.
- ^ Tsai SC, Gaylor JL (September 1966). "Testicular sterols. V. Preparation and partial purification of a microsomal prenol pyrophosphate pyrophosphohydrolase". The Journal of Biological Chemistry. 241 (17): 4043–50. PMID 4288361.
External links
edit- Farnesyl+diphosphatase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
