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F-box only protein 28 is a protein that in humans is encoded by the FBXO28 gene.[5][6]

FBXO28
Identifiers
AliasesFBXO28, CENP-30, Fbx28, F-box protein 28
External IDsOMIM: 609100 MGI: 1261890 HomoloGene: 9050 GeneCards: FBXO28
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for FBXO28
Genomic location for FBXO28
Band1q42.11Start224,114,111 bp[1]
End224,162,047 bp[1]
RNA expression pattern
PBB GE FBXO28 202272 s at fs.png

PBB GE FBXO28 202271 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001136115
NM_015176

NM_175127

RefSeq (protein)

NP_001129587
NP_055991

NP_780336

Location (UCSC)Chr 1: 224.11 – 224.16 MbChr 1: 182.31 – 182.34 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004).[supplied by OMIM][6]

ReferencesEdit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000143756 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000047539 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Seki N, Ohira M, Nagase T, Ishikawa K, Miyajima N, Nakajima D, Nomura N, Ohara O (Feb 1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain". DNA Res. 4 (5): 345–9. doi:10.1093/dnares/4.5.345. PMID 9455484.
  6. ^ a b "Entrez Gene: FBXO28 F-box protein 28".

Further readingEdit