FAM107A

Protein FAM107A is a protein that in humans is encoded by the FAM107A gene.

FAM107A
Identifiers
Aliases	FAM107A, DRR1, TU3A, family with sequence similarity 107 member A
External IDs	OMIM: 608295 MGI: 3041256 HomoloGene: 48509 GeneCards: FAM107A
Gene location (Human) Chr. Chromosome 3 (human) Band 3p14.3-p14.2 Start 58,564,117 bp End 58,627,610 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14|14 A1 Start 14,151,750 bp End 14,173,499 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Region I of hippocampus proper external globus pallidus amygdala optic nerve putamen nucleus accumbens middle frontal gyrus inferior olivary nucleus internal globus pallidus ventral tegmental area Top expressed in otolith organ utricle cerebellar vermis medial dorsal nucleus inferior colliculus globus pallidus mammillary body Region I of hippocampus proper primary motor cortex ciliary body More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding molecular function actin binding Cellular component neuron projection nucleus nuclear speck stress fiber cytoplasm focal adhesion actin cytoskeleton ruffle membrane synapse cytoskeleton plasma membrane membrane cell junction cell projection Biological process regulation of growth regulation of cell growth actin filament polymerization positive regulation of cell migration positive regulation of protein ubiquitination regulation of protein stability cellular response to nutrient levels regulation of actin cytoskeleton organization cognition actin filament bundle assembly negative regulation of focal adhesion assembly regulation of microtubule cytoskeleton organization cellular response to glucocorticoid stimulus negative regulation of long-term synaptic potentiation negative regulation of G1/S transition of mitotic cell cycle cell cycle Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11170 268709 Ensembl ENSG00000168309 ENSMUSG00000021750 UniProt O95990 Q78TU8 RefSeq (mRNA) NM_001076778 NM_001282713 NM_001282714 NM_007177 NM_183187 NM_001360337 NM_001360338 NM_001360339 RefSeq (protein) NP_001070246 NP_001269642 NP_001269643 NP_009108 NP_001269643.1 NP_001347266 NP_001347267 NP_001347268 NP_899010 Location (UCSC) Chr 3: 58.56 – 58.63 Mb Chr 14: 14.15 – 14.17 Mb PubMed search
Wikidata
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Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Kholodnyuk ID, Kozireva S, Kost-Alimova M, et al. (2006). "Down regulation of 3p genes, LTF, SLC38A3 and DRR1, upon growth of human chromosome 3-mouse fibrosarcoma hybrids in severe combined immunodeficiency mice". Int. J. Cancer. 119 (1): 99–107. doi:10.1002/ijc.21794. PMID 16432833. S2CID 27171340.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.