Ectonucleoside triphosphate diphosphohydrolase 3 is an enzyme that in humans is encoded by the ENTPD3 gene.[5][6]

ENTPD3
Identifiers
AliasesENTPD3, CD39L3, HB6, NTPDase-3, ectonucleoside triphosphate diphosphohydrolase 3
External IDsOMIM: 603161; MGI: 1321386; HomoloGene: 68171; GeneCards: ENTPD3; OMA:ENTPD3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001248
NM_001291960
NM_001291961

NM_178676

RefSeq (protein)

NP_001239
NP_001278889
NP_001278890

NP_848791

Location (UCSC)Chr 3: 40.39 – 40.43 MbChr 9: 120.37 – 120.4 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

ENTPD3 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD3 contains 4 apyrase-conserved regions which is characteristic of NTPases.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000168032Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041608Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Chadwick BP, Frischauf AM (Oct 1998). "The CD39-like gene family: identification of three new human members (CD39L2, CD39L3, and CD39L4), their murine homologues, and a member of the gene family from Drosophila melanogaster". Genomics. 50 (3): 357–67. doi:10.1006/geno.1998.5317. PMID 9676430.
  6. ^ a b "Entrez Gene: ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3".

Further reading

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