DEAD (Asp-Glu-Ala-Asp) box polypeptide 27, also known as DDX27, is a human gene.[5]

DDX27
Identifiers
AliasesDDX27, DRS1, Drs1p, PP3241, RHLP, dJ686N3.1, HSPC259, DEAD-box helicase 27
External IDsOMIM: 616621; MGI: 2385884; HomoloGene: 6431; GeneCards: DDX27; OMA:DDX27 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_017895
NM_001348187

NM_153065

RefSeq (protein)

NP_060365
NP_001335116

NP_694705

Location (UCSC)Chr 20: 49.22 – 49.24 MbChr 2: 166.86 – 166.88 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The protein encoded by this gene belongs to the family of DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, the function of which has not been determined.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000124228Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000017999Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27".

Further reading

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