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Corynebacterium glutamicum (previously known as Micrococcus glutamicus)[1] is a Gram-positive, rod-shaped bacterium that is used industrially for large-scale production of amino acids.[2] While originally identified in a screen for organisms secreting L-glutamate, mutants of C. glutamicum have also been identified that produce various other amino acids.[3]

Corynebacterium glutamicum
C glutamicum visualized using scanning electron microscopy.tif
C. glutamicum under scanning electron microscopy.
Scientific classification
Binomial name
Corynebacterium glutamicum

Due to its industrial importance, several clones of C. glutamicum have been sequenced by both industry and academic groups.[2] Furthermore, small RNA data was obtained by RNA-Seq in C. glutamicum ATCC 13032.[4]

Brevibacterium flavumEdit

Corynebacterium glutamicum ATCC 14067 was previously known as Brevibacterium flavum.[5]

See alsoEdit


  1. ^ Tatsumi, Nami; Inui, Masayuki (14 August 2012). Corynebacterium glutamicum: Biology and Biotechnology. Springer Science & Business Media. p. 336. ISBN 978-3-642-29857-8.
  2. ^ a b Kalinowski, J; Bathe, B; Bartels, D; Bischoff, N; Bott, M; et al. (4 September 2003). "The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of l-aspartate-derived amino acids and vitamins". Journal of Biotechnology. 104 (1–3): 5–25. doi:10.1016/S0168-1656(03)00154-8. PMID 12948626.
  3. ^ Zahoor A; Lindner SN; Wendisch VF (October 2012). "Metabolic Engineering of Corynebacterium glutamicum Aimed at Alternative Carbon Sources and New Products". Computational and Structural Biotechnology Journal. 3 (4): 1–11. doi:10.5936/csbj.201210004. PMC 3962153. PMID 24688664.
  4. ^ Mentz, Almut; Neshat, Armin; Pfeifer-Sancar, Katharina; Pühler, Alfred; Rückert, Christian; Kalinowski, Jörn (2013-10-19). "Comprehensive discovery and characterization of small RNAs in Corynebacterium glutamicum ATCC 13032". BMC Genomics. 14: 714. doi:10.1186/1471-2164-14-714. ISSN 1471-2164. PMC 4046766. PMID 24138339.
  5. ^ Lv, Yangyong; Juanjun, Liao; Wu, Zhanhong; Han, Shuangyan; Lin, Yin; Zheng, Suiping (February 2012). "Genome Sequence of Corynebacterium glutamicum ATCC 14067, Which Provides Insight into Amino Acid Biosynthesis in Coryneform Bacteria". Journal of Bacteriology. 194 (3): 742–743. doi:10.1128/JB.06514-11. PMC 3264075. PMID 22247536.

External linksEdit