Arf-GAP with dual PH domain-containing protein 1 is a protein that in humans is encoded by the ADAP1 gene.[5][6]

ADAP1
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesADAP1, CENTA1, GCS1L, p42IP4, Centaurin, alpha 1, ArfGAP with dual PH domains 1
External IDsOMIM: 608114; MGI: 2442201; HomoloGene: 55997; GeneCards: ADAP1; OMA:ADAP1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006869
NM_001284308
NM_001284309
NM_001284310
NM_001284311

NM_172723

RefSeq (protein)

NP_001271237
NP_001271238
NP_001271239
NP_001271240
NP_006860

n/a

Location (UCSC)Chr 7: 0.9 – 0.96 MbChr 5: 139.26 – 139.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

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Centaurin, alpha 1 has been shown to interact with:

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000105963Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000056413Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Venkateswarlu K, Oatey PB, Tavaré JM, Jackson TR, Cullen PJ (Jun 1999). "Identification of centaurin-alpha1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1". The Biochemical Journal. 340 (2): 359–63. doi:10.1042/0264-6021:3400359. PMC 1220257. PMID 10333475.
  6. ^ "Entrez Gene: CENTA1 centaurin, alpha 1".
  7. ^ Dubois T, Howell S, Zemlickova E, Aitken A (Apr 2002). "Identification of casein kinase Ialpha interacting protein partners". FEBS Letters. 517 (1–3): 167–71. doi:10.1016/s0014-5793(02)02614-5. PMID 12062430. S2CID 84792445.
  8. ^ Dubois T, Kerai P, Zemlickova E, Howell S, Jackson TR, Venkateswarlu K, Cullen PJ, Theibert AB, Larose L, Roach PJ, Aitken A (Jun 2001). "Casein kinase I associates with members of the centaurin-alpha family of phosphatidylinositol 3,4,5-trisphosphate-binding proteins". The Journal of Biological Chemistry. 276 (22): 18757–64. doi:10.1074/jbc.M010005200. PMID 11278595.
  9. ^ Dubois T, Zemlickova E, Howell S, Aitken A (Feb 2003). "Centaurin-alpha 1 associates in vitro and in vivo with nucleolin". Biochemical and Biophysical Research Communications. 301 (2): 502–8. doi:10.1016/s0006-291x(02)03010-3. PMID 12565890.
  10. ^ a b c d Zemlickova E, Dubois T, Kerai P, Clokie S, Cronshaw AD, Wakefield RI, Johannes FJ, Aitken A (Aug 2003). "Centaurin-alpha(1) associates with and is phosphorylated by isoforms of protein kinase C". Biochemical and Biophysical Research Communications. 307 (3): 459–65. doi:10.1016/s0006-291x(03)01187-2. PMID 12893243.

Further reading

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