CRISP2

Cysteine-rich secretory protein 2 is a cysteine-rich secretory protein that in humans is encoded by the CRISP2 gene.

CRISP2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2CQ7
Identifiers
Aliases	CRISP2, CRISP-2, CT36, GAPDL5, TPX1, TSP1, cysteine rich secretory protein 2
External IDs	OMIM: 187430; MGI: 98815; HomoloGene: 37756; GeneCards: CRISP2; OMA:CRISP2 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6p12.3 Start 49,692,358 bp End 49,713,590 bp
Gene location (Mouse) Chr. Chromosome 17 (mouse) Band 17 B2|17 19.54 cM Start 41,074,911 bp End 41,117,894 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm left testis right testis right uterine tube pancreatic ductal cell testicle bronchial epithelial cell minor salivary glands caput epididymis gallbladder Top expressed in seminiferous tubule spermatid spermatocyte embryo epithelium of lens muscle tissue white adipose tissue islet of Langerhans striated muscle tissue skeletal muscle tissue More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 7180 22024 Ensembl ENSG00000124490 ENSMUSG00000023930 UniProt P16562 P16563 RefSeq (mRNA) NM_001142407 NM_001142408 NM_001142417 NM_001142435 NM_001261822 NM_003296 NM_001204071 NM_009420 RefSeq (protein) NP_001135879 NP_001135880 NP_001135889 NP_001135907 NP_001248751 NP_003287 NP_001191000 NP_033446 Location (UCSC) Chr 6: 49.69 – 49.71 Mb Chr 17: 41.07 – 41.12 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

External links

• Human CRISP2 genome location and CRISP2 gene details page in the UCSC Genome Browser.

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Busso D, Cohen DJ, Hayashi M, et al. (2005). "Human testicular protein TPX1/CRISP-2: localization in spermatozoa, fate after capacitation and relevance for gamete interaction". Mol. Hum. Reprod. 11 (4): 299–305. doi:10.1093/molehr/gah156. hdl:11336/31466. PMID 15734896.
• Du Y, Huang X, Li J, et al. (2006). "Human testis specific protein 1 expression in human spermatogenesis and involvement in the pathogenesis of male infertility". Fertil. Steril. 85 (6): 1852–4. doi:10.1016/j.fertnstert.2005.11.064. PMID 16759931.