Centrosomal protein of 152 kDa, also known as Cep152, is a protein that in humans is encoded by the CEP152 gene.[5] It is the ortholog of the Drosophila melanogaster gene asterless (asl) and both are required for centriole duplication.[6]

CEP152
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCEP152, MCPH4, MCPH9, SCKL5, centrosomal protein 152
External IDsOMIM: 613529; MGI: 2139083; HomoloGene: 37159; GeneCards: CEP152; OMA:CEP152 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001194998
NM_014985

NM_001081091

RefSeq (protein)

NP_001181927
NP_055800

NP_001074560

Location (UCSC)Chr 15: 48.71 – 48.81 MbChr 2: 125.41 – 125.47 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000103995Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000068394Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: centrosomal protein 152kDa".
  6. ^ Blachon S, Gopalakrishnan J, Omori Y, Polyanovsky A, Church A, Nicastro D, Malicki J, Avidor-Reiss T (December 2008). "Drosophila asterless and vertebrate Cep152 Are orthologs essential for centriole duplication". Genetics. 180 (4): 2081–94. doi:10.1534/genetics.108.095141. PMC 2600943. PMID 18854586.
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Further reading

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