Cell division cycle 26 is a protein that in humans is encoded by the CDC26 gene.[5]

CDC26
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCDC26, ANAPC12, APC12, C9orf17, cell division cycle 26
External IDsOMIM: 614533; MGI: 1913690; HomoloGene: 16410; GeneCards: CDC26; OMA:CDC26 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_139286

NM_139291
NM_001368241

RefSeq (protein)

NP_644815
NP_644815.1

NP_647452
NP_001355170

Location (UCSC)Chr 9: 113.26 – 113.28 MbChr 4: 62.3 – 62.33 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc26, a component of cell cycle anaphase-promoting complex (APC). APC is composed of a group of highly conserved proteins and functions as a cell cycle-regulated ubiquitin-protein ligase. APC thus is responsible for the cell cycle regulated proteolysis of various proteins. [provided by RefSeq, Jul 2008].

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  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Anaphase-promoting complex subunit CDC26

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000176386Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000066149Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Cell division cycle 26". Retrieved 2018-10-16.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.