Coiled-coil domain-containing protein 85B is a protein that in humans is encoded by the CCDC85B gene .[5] [6] [7]
Function
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Hepatitis delta virus (HDV) is a pathogenic human virus whose RNA genome and replication cycle resemble those of plant viroids . Delta-interacting protein A (DIPA), a cellular gene product, has been found to have homology to hepatitis delta virus antigen (HDAg). DIPA interacts with the viral antigen, HDAg, and can affect HDV replication in vitro [7]
Interactions
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CCDC85B has been shown to interact with:
References
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^ a b c GRCh38: Ensembl release 89: ENSG00000175602 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000095098 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Brazas R, Ganem D (Oct 1996). "A cellular homolog of hepatitis delta antigen: implications for viral replication and evolution". Science . 274 (5284): 90–4. Bibcode :1996Sci...274...90B . doi :10.1126/science.274.5284.90 . PMID 8810253 . S2CID 20743492 . ^ Bezy O, Elabd C, Cochet O, Petersen RK, Kristiansen K, Dani C, et al. (Mar 2005). "Delta-interacting protein A, a new inhibitory partner of CCAAT/enhancer-binding protein beta, implicated in adipocyte differentiation" . The Journal of Biological Chemistry . 280 (12): 11432–8. doi :10.1074/jbc.M411741200 PMID 15644333 . ^ a b "Entrez Gene: CCDC85B coiled-coil domain containing 85B" .^ a b c d Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, et al. (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 .
External links
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Further reading
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Robertson HD (Oct 1996). "How did replicating and coding RNAs first get together?". Science . 274 (5284): 66–7. Bibcode :1996Sci...274...66R . doi :10.1126/science.274.5284.66 . PMID 8848724 . S2CID 37715470 . Long M, de Souza SJ, Gilbert W (May 1997). "Delta-interacting protein A and the origin of hepatitis delta antigen". Science . 276 (5313): 824–5. doi :10.1126/science.276.5313.824 . PMID 9115212 . Schumacher B, Schertel C, Wittenburg N, Tuck S, Mitani S, Gartner A, et al. (Feb 2005). "C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage" . Cell Death and Differentiation . 12 (2): 153–61. doi :10.1038/sj.cdd.4401539 PMID 15605074 . Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, et al. (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 . Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, et al. (May 2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration" . Cell . 125 (4): 801–14. doi :10.1016/j.cell.2006.03.032 PMID 16713569 . S2CID 13709685 . Du X, Wang Q, Hirohashi Y, Greene MI (Dec 2006). "DIPA, which can localize to the centrosome, associates with p78/MCRS1/MSP58 and acts as a repressor of gene transcription". Experimental and Molecular Pathology . 81 (3): 184–90. doi :10.1016/j.yexmp.2006.07.008 . PMID 17014843 .
