Butyrate—acetoacetate CoA-transferase

In enzymology, a butyrate-acetoacetate CoA-transferase (EC 2.8.3.9) is an enzyme that catalyzes the chemical reaction

butyrate-acetoacetate CoA-transferase
Identifiers
EC no.2.8.3.9
CAS no.66231-37-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
butanoyl-CoA + acetoacetate butanoate + acetoacetyl-CoA

Thus, the two substrates of this enzyme are butanoyl-CoA and acetoacetate, whereas its two products are butanoate and acetoacetyl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is butanoyl-CoA:acetoacetate CoA-transferase. Other names in common use include butyryl coenzyme A-acetoacetate coenzyme A-transferase, and butyryl-CoA-acetoacetate CoA-transferase.

References

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  • Barker HA, Jeng IM, Neff N, Robertson JM, Tam FK, Hosaka S (1978). "Butyryl-CoA:acetoacetate CoA-transferase from a lysine-fermenting Clostridium". J. Biol. Chem. 253 (4): 1219–25. PMID 624727.