Blautia wexlerae is an anaerobic and gram-positive bacteria that lives in the human intestine.[1][2] Very little is known about this bacteria and its effects on human health.

Blautia wexlerae
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Bacillota
Class: Clostridia
Order: Eubacteriales
Family: Lachnospiraceae
Genus: Blautia
Species:
B. wexlerae
Binomial name
Blautia wexlerae
Liu et al. 2008

One study found that intestinal B. wexlerae descreases obesity and diabetes in Japanese adults. It also found that B. wexlerae produces acetylcholine and carbohydrate metabolites (ex. succinate, lactate, acetate). These may modify the gut environment, including the bacterial and SCFA composition of the gut microbiota. Thus, B. wexlerae may offer various, numerous, and diverse benefits for health maintenance.[3]

B. wexlerae has also shown to be positively associated with children with higher cognitive function scores.[4]

References edit

  1. ^ Podstawka, Adam. "Blautia wexlerae Walcc: 14507 | Type strain | DSM 19850, ATCC BAA 1564, JCM 17041, KCTC 5965, WAL 14507 | BacDiveID:18075". bacdive.dsmz.de. Retrieved 23 May 2023.
  2. ^ "Summary of Blautia wexlerae DSM 19850, version 27.0". biocyc.org. Retrieved 22 May 2023.
  3. ^ Hosomi, Koji; Saito, Mayu; Park, Jonguk; Murakami, Haruka; Shibata, Naoko; Ando, Masahiro; Nagatake, Takahiro; Konishi, Kana; Ohno, Harumi; Tanisawa, Kumpei; Mohsen, Attayeb; Chen, Yi-An; Kawashima, Hitoshi; Natsume-Kitatani, Yayoi; Oka, Yoshimasa; Shimizu, Hidenori; Furuta, Mari; Tojima, Yoko; Sawane, Kento; Saika, Azusa; Kondo, Saki; Yonejima, Yasunori; Takeyama, Haruko; Matsutani, Akira; Mizuguchi, Kenji; Miyachi, Motohiko; Kunisawa, Jun (18 August 2022). "Oral administration of Blautia wexlerae ameliorates obesity and type 2 diabetes via metabolic remodeling of the gut microbiota". Nature Communications. 13 (1): 4477. Bibcode:2022NatCo..13.4477H. doi:10.1038/s41467-022-32015-7. PMC 9388534. PMID 35982037.
  4. ^ Bonham, Kevin S.; Fahur Bottino, Guilherme; McCann, Shelley Hoeft; Beauchemin, Jennifer; Weisse, Elizabeth; Barry, Fatoumata; Cano Lorente, Rosa; The RESONANCE Consortium; Huttenhower, Curtis; Bruchhage, Muriel; D’Sa, Viren; Deoni, Sean; Klepac-Ceraj, Vanja (2023-12-22). "Gut-resident microorganisms and their genes are associated with cognition and neuroanatomy in children". Science Advances. 9 (51): eadi0497. doi:10.1126/sciadv.adi0497. ISSN 2375-2548. PMC 10745691. PMID 38134274.