Benjamin Levine Ebert is the Chair of Medical Oncology at the Dana–Farber Cancer Institute and the George P. Canellos, MD and Jean S. Canellos Professor of Medicine at Harvard Medical School.
Benjamin L. Ebert | |
|---|---|
| Born | Boston |
| Academic background | |
| Education | BSc, Williams College PhD, 1995, University of Oxford MD, 1999, Harvard Medical School |
| Thesis | Transcriptional regulation of the LDH-A and erythropoietin genes by hypoxia (1999) |
| Academic work | |
| Institutions | Harvard Medical School Dana–Farber Cancer Institute |
Early life and education edit
Ebert was born in Boston Lying-In Hospital[1] to parents Michael and Ellen Ebert. His father was the Chair of the department of psychiatry at Vanderbilt University School of Medicine while his mother was an artist.[2] Due to his fathers position, Ebert and his family lived in Baltimore, Maryland, and Bethesda, Tennessee.[1] While in Tennessee, Ebert was enrolled at the University School of Nashville where he was ranked nationally in table tennis.[2] During high school, he also worked in the laboratory of Daryl Granner and studied gene regulation and diabetes.[3]
Following high school, Ebert received a bachelor's degree from Williams College. As a senior, he was presented with the college's Good Citizen award for his involvement in various community projects over the years.[4] Ebert was also elected president of the Williams juggling club and competed in cycling and running.[3] In 1991, Ebert was named one of 32 Rhodes Scholar to study at the University of Oxford.[2] Upon returning to North America, Ebert enrolled at Harvard Medical School (HMS) and worked with Frank Bunn whom he later listed as the primary reason for pursuing a career in hematology.[1] He graduated from HMS in 1999 and then completed his internship and residency at Massachusetts General Hospital in 2001. He then went on to complete his clinical fellowship in hematology and oncology at Dana–Farber Cancer Institute (DFCI).[5]
Career edit
During his tenure at DFCI, Ebert described the genomic landscape of adult myelodysplastic syndromes and identified RPS14 as a key gene for deletion 5q MDS.[5] In 2011, Ebert was elected to the American Society for Clinical Investigation.[6] In 2014, Ebert collaborated with William Kaelin on a study that found that lenalidomide, a cancer drug, targeted two proteins, IKZF1 and IFZF3, for destruction. As such, he discovered the molecular basis of lenalidomide activity in MDS as well as multiple myeloma.[7] As a result of his research, Ebert was the recipient of the 2017 William Dameshek Prize from the American Society of Hematology.[5] He also earned a National Cancer Institute Outstanding Investigator Award for his ongoing progressive research.[8]
In 2018, Ebert, was elected a member of the National Academy of Medicine for his "contributions to understanding the genetics and biology of myeloid malignancies, to the characterization of clonal hematopoiesis, and for elucidating the mechanism of action of thalidomide and its analogs."[9] He was also named a Howard Hughes Medical Institute Investigator, which granted him seven years of funding to research genetics, biology, and therapy of myeloid malignancies.[10] In the same year, Ebert, Kenneth Anderson, and Irene Ghobrial were granted three years of funding from the Dr. Miriam and Sheldon G. Adelson Medical Research Foundation to study ways to prevent multiple myeloma from precursor states.[11] In 2021, Ebert was recognized with the Sjöberg Prize for Cancer Research from the Royal Swedish Academy of Sciences.[12]
References edit
- ^ a b c "Pulling Back the Curtain: Benjamin Ebert, MD, PhD". ASH Clinical News. February 1, 2015. Retrieved January 2, 2022.
- ^ a b c Smith, Tammie (December 9, 1991). "Nashvillian chosen as Rhodes Scholar". The Tennessean. Retrieved January 2, 2022 – via newspapers.com.
- ^ a b "Benjamin Ebert, MD, PhD: HHMI Investigator". Howard Hughes Medical Institute. 2018. Retrieved January 2, 2022.
- ^ "Good Citizen award". The Berkshire Eagle. January 30, 1992. Retrieved January 2, 2022 – via newspapers.com.
- ^ a b c "The American Society of Hematology Honors Benjamin L. Ebert, MD, PhD, with the 2017 William Dameshek Prize". American Society of Hematology. August 24, 2017. Retrieved January 2, 2021.
- ^ "Benjamin L. Ebert, MD, PhD". American Society for Clinical Investigation. Retrieved January 2, 2022.
- ^ Davis, Nicole (April 30, 2021). "Disappearing Act: Eliminating Cancer's Building Blocks". Dana–Farber Cancer Institute. Retrieved January 2, 2022.
- ^ "Four Dana-Farber researchers awarded prestigious 'outstanding investigator awards' by National Cancer Institute". Dana–Farber Cancer Institute. June 5, 2017. Retrieved January 2, 2022.
- ^ "Two Dana-Farber faculty elected to prestigious National Academy of Medicine". Dana–Farber Cancer Institute. October 15, 2018. Retrieved January 2, 2022.
- ^ "Dana-Farber Medical Oncology Chair named Howard Hughes Medical Institute Investigator". Dana–Farber Cancer Institute. May 23, 2018. Retrieved January 2, 2022.
- ^ "Three Dana-Farber researchers awarded new grant to accelerate multiple myeloma research". Dana–Farber Cancer Institute. March 8, 2018. Retrieved January 2, 2022.
- ^ "Dana-Farber Oncologist Benjamin Ebert, MD, PhD, Awarded Sjöberg Prize for Cancer Research". The ASCO Post. April 10, 2021. Retrieved January 2, 2022.