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Type antihistamine, allergy Medication
Inception 1946 (1946)
Manufacturer Johnson & Johnson
Available Available

Benadryl is a brand name for a number of different antihistamine medications used to treat allergies.

In the United States and Canada, it is the first-generation antihistamine diphenhydramine. Diphenhydramine can also cause sleepiness. The product is not recommended for use in children under 6[1] where it has caused fatalities.[2][3]

Some products marketed in Australia and New Zealand as a cough medicine with the Benadryl name contain diphenhydramine.[4] In the United Kingdom, the active component of Benadryl is often the antihistamine acrivastine[5] or cetirizine.[6]

Benadryl is available for by mouth or topical use. It is marketed without a prescription by Johnson & Johnson subsidiary McNeil Consumer Healthcare. Before 2007, Benadryl was marketed by Pfizer Consumer Healthcare (originally Warner–Lambert).[7][8]


  1. ^ "Benadryl oral : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD". WebMD. Retrieved 2017-02-04. 
  2. ^ A mother’s warning after babysitter allegedly gives infant a lethal dose of Benadryl By Lindsey Bever, Washington Post, June 7, 2016
  3. ^ Nine JS, Rund CR. (March 2006). "Fatality from diphenhydramine monointoxication: a case report and review of the infant, pediatric, and adult literature". Am J Forensic Med Pathol. 27 (1): 36–41. doi:10.1097/ PMID 16501346. 
  4. ^ "ARTG, PI and CMI results searching for Benadryl". Department of Health Therapeutic Goods Administration, Australia. 
  5. ^ "Benadryl Allergy Relief - Summary of Product Characteristics". eMC. 21 May 2016. Retrieved 11 December 2016. 
  6. ^ "Benadryl Allergy One A Day 10mg Tablets - Summary of Product Characteristics". eMC. 11 November 2015. Retrieved 11 December 2016. 
  7. ^ "Johnson & Johnson to Acquire Pfizer Consumer Healthcare" (Press release). Johnson & Johnson. June 26, 2006. Retrieved November 19, 2009. 
  8. ^ "Johnson & Johnson Completes Acquisition Of Pfizer Consumer Healthcare" (Press release). Johnson & Johnson. December 20, 2006. Retrieved November 19, 2009. 

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