Barry Austin Gusterson (born 24 October 1946) is a British pathologist who has been Professor of Pathology at the University of Glasgow since 2000 and Head of Forensic Medicine and Forensic Science, since 2006. Prior to this he was Founding Director of the Toby Robins Breakthrough Breast Cancer Research Centre at the Institute of Cancer Research and Professor of Pathology and Head of the Section of Molecular Pathology at the Institute of Cancer Research.

Barry Austin Gusterson
Born (1946-10-24) 24 October 1946 (age 77)[3]
Alma materRoyal Dental Hospital, St Bartholomew's Hospital and Institute of Cancer Research[3]
Known forInitiating the Toby Robins Cancer Research Centre in London [4] and the Wolfson Wohl Cancer Centre in Glasgow[5][6]. Work on EGFR in head and neck cancer [7][8] and studies of HER2 in breast cancer[9] and in human breast development[10][11]
Spouse
Ann Josephine Davies
(m. 1972)
[3]
Awards
  • Oakley Lecturer (1985)[1]
  • Doniach Lecturer (2009)[2]
Scientific career
FieldsPathology, Cancer
Institutions
Thesis In Vitro Study of Tumour Associated Opiate Receptors and Tumour Derived Opioid Activity [3]  (1980)

Education

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Gusterson was educated at Colchester Royal Grammar School and obtained a BSc in Physiology at St Bartholomew's Hospital. He then earned a dental degree at the Royal Dental Hospital and a medical degree at St Bartholomew’s Hospital. He also studied at the Institute for Cancer Research. He obtained a PhD on opiate receptors at the Ludwig Institute, and his MRCPath, while training at the Royal Marsden Hospital.

Career

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Gusterson held posts in medicine and surgery at St Bartholow’s Hospital and the Royal Devon and Exeter Hospital and was appointed as Professor of Histopathology at the Institute of Cancer Research and Consultant at the Royal Marsden Hospital in 1986. Whilst at the Institute he held a number of senior positions, including Chairman of the Section of Cell Biology and Experimental Pathology. He initiated the concept to build the first dedicated breast cancer research centre and was appointed Founding Director of the Toby Robins, Breakthrough Breast Cancer Research Centre in 1998.[12][non-primary source needed] In 2000 he moved to Glasgow University, where he held a number of positions as Professor of Pathology, Head of Forensic Science and Medicine, initiator and Director of the Glasgow Biobank.[13][non-primary source needed] As Associate Dean for Research in the Medical faculty and Head of Cancer Sciences he restructured cancer sciences, which brought Glasgow up to 4th in the UK in the Research Assessment Exercise. He chaired the pan-Glasgow pathology Committee that resulted in the unification of all pathology departments across Glasgow and Clyde into a new purpose built building at the Southern General Hospital. Gusterson retired in 2011 and became a Trustee for Moorfield’s Eye Charity and a member of Council for St George's, University of London.[14]

Research

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Gusterson’s interests have been predominantly aimed at understanding the biology of head and neck cancer and breast cancer, with some earlier studies on soft tissue sarcomas. He has studied normal breast and breast development.[citation needed] Since retiring his research interests continue in these areas.

Gusterson initiated two cancer centres, which developed as major fund-raising projects in which he played a key role as the clinical lead. These resulted in the building of the Toby Robins Breakthrough Breast Cancer Research Centre at the Institute of Cancer Research in London[15] and the Wolfson Wohl Cancer Research Centre at Glasgow University[citation needed].

Notes

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  1. ^ "Oakley Lecture". www.pathsoc.org. Pathological Society. Retrieved 9 July 2024.
  2. ^ "Doniach Lecture". www.pathsoc.org. Pathological Society. Retrieved 9 July 2024.
  3. ^ a b c d e "Gusterson, Prof. Barry Austin". Who's Who. Vol. 2024 (online Oxford University Press ed.). Oxford: A & C Black. (Subscription or UK public library membership required.)
  4. ^ "Breakthrough Breast Cancer". Wikipedia, The Free Encyclopedia. Retrieved 9 July 2024.
  5. ^ "A Significant Medical History > 20th Century > 1948-2018 > Pathology". University of Glasgow. Retrieved 9 July 2024.
  6. ^ "Huge Boost for the Beatson Pebble Appeal", University of Glasgow - University News, 26 March 2009, retrieved 9 July 2024
  7. ^ Cowley, G. P.; Smith, J. A.; Gusterson, B. A. (1986). "Increased EGF receptors on human squamous carcinoma cell lines". British journal of cancer. 53 (2): 223–229. doi:10.1038/bjc.1986.39. PMC 2001344. PMID 2420349.
  8. ^ Ozanne, B.; Richards, C. S.; Hendler, F.; Burns, D.; Gusterson, B. A. (1986). "Over-expression of the EGF receptor is a hallmark of squamous cell carcinomas". The Journal of pathology. 149 (1): 9–14. doi:10.1002/path.1711490104. PMID 2425067.
  9. ^ Gusterson, B .A.; Gelber, R. D.; Goldhirsch, A.; Price, K. N.; Säve-Söderborgh, J.; Anbazhagan, R.; Styles, J.; Rudenstam, C. M.; Golouh, R.; Reed, R. (1992). "Prognostic importance of c-erbB-2 expression in breast cancer. International (Ludwig) Breast Cancer Study Group". Journal of clinical oncology. 10 (7): 1049–1056. doi:10.1200/JCO.1992.10.7.1049. PMID 1351538.
  10. ^ Anbazhagan, R.; Osin, P. P.; Bartkova, J.; Nathan, B.; Lane, E. B.; Gusterson, B. A. (1998). "The development of epithelial phenotypes in the human fetal and infant breast". The Journal of pathology. 184 (2): 197–206. doi:10.1002/(SICI)1096-9896(199802)184:2<197::AID-PATH992>3.0.CO;2-J. PMID 9602712.
  11. ^ Howard, B. A.; Gusterson, B. A. (2000). "Human breast development". Journal of mammary gland biology and neoplasia. 5 (2): 119–137. doi:10.1023/a:1026487120779. PMID 11149569.
  12. ^ "Founding Fellows". Breakthrough Breast Cancer. Retrieved 21 February 2014.
  13. ^ "Barry Gusterson". The University of Glasgow Story. Glasgow University. Retrieved 21 February 2014.
  14. ^ "Professor Barry Gusterson". St George's. St George's, University of London. Archived from the original on 21 February 2014. Retrieved 21 February 2014.[non-primary source needed]
  15. ^ "History". Breakthrough Breast Cancer. Archived from the original on 28 February 2014. Retrieved 21 February 2014.[non-primary source needed]
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