BB2 may refer to:
- Baahubali 2: The Conclusion, an Indian film directed by S. S. Rajamouli
- Bhool Bhulaiyaa 2, a 2022 Indian Hindi language film directed by Anees Bazmee
- USS Massachusetts (BB-2), a United States battleship from 1896 to 1919
- Bad Boys II, a 2003 action comedy movie starring Martin Lawrence and Will Smith
- Gastrin-releasing peptide receptor (GRPR), also known as BB2
- Big Brother 2, a television programme in various versions
- BB2, a postcode district in the BB postcode area
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