Aquaporin-5 (AQP-5) is a protein that in humans is encoded by the AQP5 gene.[5][6]

AQP5
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesAQP5, AQP-5, PPKB, aquaporin 5
External IDsOMIM: 600442; MGI: 106215; HomoloGene: 20398; GeneCards: AQP5; OMA:AQP5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001651

NM_009701

RefSeq (protein)

NP_001642

NP_033831

Location (UCSC)Chr 12: 49.96 – 49.97 MbChr 15: 99.49 – 99.49 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Aquaporin-5 (AQP-5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin-5 plays a role in the generation of saliva, tears and pulmonary secretions.[6] AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13.[6]

References

edit
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000161798Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000044217Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Lee MD, Bhakta KY, Raina S, Yonescu R, Griffin CA, Copeland NG, Gilbert DJ, Jenkins NA, Preston GM, Agre P (Jun 1996). "The human Aquaporin-5 gene. Molecular characterization and chromosomal localization". J Biol Chem. 271 (15): 8599–604. doi:10.1074/jbc.271.15.8599. PMID 8621489.
  6. ^ a b c "Entrez Gene: AQP5 aquaporin 5".

Further reading

edit
edit

This article incorporates text from the United States National Library of Medicine, which is in the public domain.