- Most famously, a town near which one or more rulers of Damascus named Ben-hadad were defeated by the Israelites and in which the Damascene king and his surviving soldiers found a safe place of retreat (1 Kings 20:26-30; 2 Kings 13:17, 24-25). Just before his death, the prophet Elisha predicted:
- "The arrow of the Lord’s deliverance and the arrow of deliverance from Syria; for you must strike the Syrians at Aphek till you have destroyed them."
- A place at which the Bible states that the Philistines had encamped, while the Israelites pitched in Eben-Ezer, before the Battle of Aphek in which the sons of Eli were killed (I Samuel 4:1–ff.)
- A city of the Tribe of Issachar, near to Jezreel, in the north of the Sharon plain. The scene, according to the Bible; of another encampment of the Philistines, which led to the defeat and death of Saul.
- Aphik, a city of the tribe of Asher, identified as either Tel Afek near Haifa, or Afqa in Lebanon.
Since the turn of the 20th century the predominant opinion was that the location of all these battles is one and the same, and that the town lay east of the Jordan. Initially it was thought that the name is preserved in the now depopulated village of Fiq near Kibbutz Afik, three miles east of the Sea of Galilee, where an ancient mound, Tell Soreg, had been identified. Excavations by Moshe Kochavi and Pirhiya Beck in 1987-88 have indeed discovered a fortified 9th- and 8th-century BCE settlement, probably Aramean, but Kochavi considered it to be too small to serve the role ascribed to Aphek in the Bible. The site most favoured now by the archaeologists is Tel 'En Gev/Khirbet el-'Asheq, a mound located within Kibbutz Ein Gev.
A more recent theory has focused on regarding this same Aphek also as the scene of the two battles against the Philistines[dubious ] mentioned by the Bible - the supposition being that the Syrians[dubious ] were invading Israel from the western side, which was their most vulnerable.
Since most scholars agree that there were more than one Aphek, C.R. Conder identified the Aphek of Eben-Ezer  with a ruin (Khirbet) some 3.7 miles (6 km) distant from Dayr Aban (believed to be Eben-Ezer), and known by the name Marj al-Fikiya; the name al-Fikiya being an Arabic corruption of Aphek. Eusebius, when writing about Eben-ezer in his Onomasticon, says that it is "the place from which the Gentiles seized the Ark, between Jerusalem and Ascalon, near the village of Bethsamys (Beit Shemesh)," a locale that corresponds with Conder's identification.
- 2 Kings 13:17: Douai Rheims translation
- 2 Kings 13:17
- The Golan Heights: A Battlefield of the Ages, LA Times, 11 September 1988
- Shuichi Hasegawa, Aram and Israel during the Jehuite Dynasty, Tel Soreg, p 72
- Avraham Negev, Shimon Gibson (2001). Aphek (c). Archaeological Encyclopedia of the Holy Land. New York: Continuum. p. 39. ISBN 0-8264-1316-1.
- The account in 1 Samuel 4:1 of the battle at Aphek and Eben-ezer
- North, Robert (1960). "Ap(h)eq(a) and 'Azeqa". Biblica. 41 (1): 61–63. JSTOR 42637769.
- Eusebius Werke, Erich Klostermann (ed.), Leipig 1904, p. 33,24.