Alpha-eudesmol synthase

α-Eudesmol synthase (EC 4.2.3.85) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (α-eudesmol-forming).[1] This enzyme catalyses the following chemical reaction

α-eudesmol synthase
Identifiers
EC no.4.2.3.85
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins
(2E,6E)-farnesyl diphosphate + H2O α-eudesmol + diphosphate

The recombinant enzyme from ginger (Zingiber zerumbet) gives β-eudesmol, 10-epi-γ-eudesmol, α-eudesmol and aristolene.

References

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  1. ^ Yu F, Harada H, Yamasaki K, Okamoto S, Hirase S, Tanaka Y, Misawa N, Utsumi R (March 2008). "Isolation and functional characterization of a β-eudesmol synthase, a new sesquiterpene synthase from Zingiber zerumbet Smith". FEBS Letters. 582 (5): 565–72. doi:10.1016/j.febslet.2008.01.020. PMID 18242187.
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