Alpha,alpha-trehalose synthase

Alpha,alpha-trehalose synthase (EC 2.4.1.245, trehalose synthase, trehalose synthetase, UDP-glucose:glucose 1-glucosyltransferase, TreT, PhGT) is an enzyme with systematic name ADP-glucose:D-glucose 1-alpha-D-glucosyltransferase.[1][2] This enzyme catalyses the following chemical reaction

Alpha,alpha-trehalose synthase
Identifiers
EC no.2.4.1.245
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
ADP-glucose + D-glucose alpha,alpha-trehalose + ADP

This enzyme requires Mg2+ for maximal activity.

References

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  1. ^ Qu Q, Lee SJ, Boos W (November 2004). "TreT, a novel trehalose glycosyltransferring synthase of the hyperthermophilic archaeon Thermococcus litoralis". The Journal of Biological Chemistry. 279 (46): 47890–7. doi:10.1074/jbc.m404955200. PMID 15364950.
  2. ^ Ryu SI, Park CS, Cha J, Woo EJ, Lee SB (April 2005). "A novel trehalose-synthesizing glycosyltransferase from Pyrococcus horikoshii: molecular cloning and characterization". Biochemical and Biophysical Research Communications. 329 (2): 429–36. doi:10.1016/j.bbrc.2005.01.149. PMID 15737605.
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