Ali Khademhosseini (born October 30, 1975, Tehran, Iran) is the Levi Knight Endowed Professor at the University of California-Los Angeles. He holds a multi-departmental professorship in Bioengineering, Radiology, Chemical, and Biomolecular Engineering. He is the Director of Center for Minimally Invasive Therapeutics (C-MIT). Previously, he was a Professor at Harvard Medical School, a faculty member at the Harvard-MIT Division of Health Sciences and Technology (HST), and the Wyss Institute for Biologically Inspired Engineering. Dr. Khademhosseini is also an Associate Editor for ACS Nano. He was a standing member of the NIH BTSS (Bioengineering, Technology and Surgical Sciences) study section. He has been cited >44,000 times and has an H-index of 110. Also, he has given over >250 invited seminars and keynote lectures. In 2014, 2015, 2016, 2017 and 2018 he was also selected by Thomson Reuters as one of the World's Most Influential Minds.
Khademhosseini in 2008
|Born||October 30, 1975|
|Alma mater||Massachusetts Institute of Technology, University of Toronto|
|Awards||American Association for the Advancement of Science (AAAS) Fellow (2014)
National Academy of Sciences Kavli Frontiers of Science Fellow (2012) Presidential Early Career Award for Scientists and Engineers (2011) Society for Biomaterials Young Investigator Award (2011) TERMIS-NA Young Investigator Award (2010); American Institute for Chemical Engineers (AIChE) Allan F. Colburn Award (2010); ACS Colloid and Surface Science Division Unilever Award (2010); Office of Naval Research Young Investigator Award (2010); Association for Lab Automation (ALA) Innovation Award (2010); International Academy for Medical and Biological Engineering (IAMBE) Award for Young Faculty Members (2009); University of Toronto Engineering alumni’s class of 7T6 award (2009); NSF Career Award (2009); IEEE/EMBS Early career award (2008); Technology Review Magazine TR35 Top Young Innovator (2007); BMW Scientific Award (2007); Coulter Foundation Early Career (2006)-national award for biomedical engineering; Outstanding Researcher in Polymer Science by OMNOVA / MIT (2005); Outstanding Research by Biomedical Engineering Society (2005)- national award;Outstanding Research Mentor at MIT (2004)- university award for mentoring;
|Fields||Biomedical Engineering, Biomaterials, Tissue Engineering|
|Institutions||University of California, Los Angeles|
|Doctoral advisor||Robert S. Langer|
Background and Personal LifeEdit
Khademhosseini was born in Tehran, Iran, and grew up in Toronto, Canada. He received his Ph.D. in bioengineering from MIT under the supervision of Robert S. Langer (2005), and MASc (2001) and BASc (1999) degrees from University of Toronto both in chemical engineering.
Contributions to Medicine and ScienceEdit
Khademhosseini has pioneered the design and development of a variety of hydrogels for regenerative medicine and medical device applications. These hydrogels encompass light-sensitive naturally-derived proteins, shear-thinning biomaterial gels, and surgical sealants, each of which has opened new horizons for tissue engineering, minimally invasive medical procedures, and advanced biomedicine.
Khademhosseini has developed the usage of a photocrosslinkable gelatin derivatives. Gelatin methacryloyl (GelMA) hydrogels have been widely used for various biomedical applications, due to their suitable biological properties, and tunable physical properties. Three dimensional (3D) GelMA hydrogels closely resemble the native extracellular matrix (ECM), due to the presence of cell-binding sites, and matrix metalloproteinase responsive peptide motifs, which allow cells to remodel and proliferate within the GelMA-based scaffolds. A second class of hydrogels pioneered by the group is a nanosilicate-based shear thinning gel that could be easily injected in a minimally invasive medical procedure.
Khademhosseini also developed ‘organ-on-a-chip’ systems that aim to mimic human responses to various chemicals in vitro. By merging the advances in microfluidics with microfabrication technologies, he has introduced novel platforms that lead to the creation of organ functions on a single chip. Within these platforms, microengineering enables precise control over the cellular microenvironment, whereas microfluidics provides an ability to perfuse the constructs on a chip and to connect individual sections with each other. This approach results in microsystems that may better represent the in vivo environment. These organ-on-a-chip platforms can be utilized for developing disease models as well as for conducting drug testing studies.
Khademhosseini is a recipient of MIT's Outstanding Undergraduate mentor award (2004) and Brigham Women's Hospital senior faculty mentor award (2016). Over 40 of his previous trainees and fellows have gone into academia as faculty at institutions including Harvard University-Massachusetts General Hospital, Brigham and Women's Hospital, Johns Hopkins University, University of California Los Angeles, University of California-Riverside, Arizona State University, Texas A&M University, University of Pittsburgh, INSERM, Northeastern University, Hanyang University, Singapore National University, and Tsinghua University.
Awards and HonorsEdit
Khademhosseini's interdisciplinary research has been recognized by over 40 major national and international awards. He is a recipients of the 2011 Presidential Early Career Award for Scientists and Engineers (PECASE) by President Barack Obama. He has received early career awards from three major engineering discipline societies: electrical (IEEE Engineering in Medicine and Biology award / IEEE Nanotechnology award), chemical (AIChE Colburn award) and mechanical engineering (ASME YC Fung award). In addition, he has received the young investigator awards of the Society for Biomaterials and the Tissue Engineering and Regenerative Medicine International Society-North America. He has also received the American Chemical Society's Viktor K. Lamer award and the Unilever award and has been recognized by major governmental awards including the NSF Career award and the Office of Naval Research young investigator award.
- "Ali Khademhosseini Ph.D. | BE". www.bioeng.ucla.edu. Retrieved 2018-01-07.
- "Editorial Board". pubs.acs.org. Retrieved 2018-03-03.
- "Ali Khademhosseini - Google Scholar Citations". scholar.google.com. Retrieved 2017-09-12.
- "The World's Most Influential Scientific Minds 2015-Thomson Reuters (2016).pdf | Citation | Science". Scribd. Retrieved 2018-03-03.
- "President Obama Honors Outstanding Early-Career Scientists". Office of the Press Secretary. 2011-09-26. Retrieved 26 September 2011.
- Harvard-MIT faculty profile
- TR35 profile
- Regenerate tissue engineering conference
- Lab on a Chip
- U of T engineering speaker
- Microengineering the cellular environment
- Khademhosseini wins the Coulter Foundation Early Career Award
- Scholarly works by Khademhosseini
- HST faculty wins the BMW Scientific award
- List of Iranian Scientist and Scholars