Ankyrin repeat and SOCS box protein 13 is a protein that in humans is encoded by the ASB13 gene.[4][5]

ASB13
Identifiers
AliasesASB13, ankyrin repeat and SOCS box containing 13
External IDsOMIM: 615055; MGI: 2145525; HomoloGene: 11666; GeneCards: ASB13; OMA:ASB13 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_024701

NM_001267724
NM_178283

RefSeq (protein)

NP_078977

NP_001254653
NP_840068

Location (UCSC)n/aChr 13: 3.68 – 3.7 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length sequences are not known.[5]

References

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  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033781Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ (Jun 2002). "The SOCS box: a tale of destruction and degradation". Trends Biochem Sci. 27 (5): 235–41. doi:10.1016/S0968-0004(02)02085-6. PMID 12076535.
  5. ^ a b "Entrez Gene: ASB13 ankyrin repeat and SOCS box-containing 13".
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Further reading

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