The Rho GTPase activating protein 31 is encoded in humans by the ARHGAP31 gene. It is a Cdc42 /Rac1 GTPase regulator.[ 5]
ARHGAP31 encodes a GTPase-activating protein (GAP). A variety of cellular processes are regulated by Rho GTPases which cycle between an inactive form bound to GDP and an active form bound to GTP . This cycling between inactive and active forms is regulated by guanine nucleotide exchange factors and GAPs. The encoded protein is a GAP shown to regulate two GTPases involved in protein trafficking and cell growth .[ 5]
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This article incorporates text from the United States National Library of Medicine , which is in the public domain .
