Ankyrin repeat domain-containing protein 23 is a protein that in humans is encoded by the ANKRD23 gene.[5][6]

ANKRD23
Identifiers
AliasesANKRD23, DARP, MARP3, ankyrin repeat domain 23
External IDsOMIM: 610736; MGI: 1925571; HomoloGene: 14025; GeneCards: ANKRD23; OMA:ANKRD23 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_144994

NM_153502
NM_001310521

RefSeq (protein)

NP_659431

NP_001297450
NP_705722

Location (UCSC)Chr 2: 96.82 – 96.86 MbChr 1: 36.57 – 36.58 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene is a member of the muscle ankyrin repeat protein (MARP) family and encodes a protein with four tandem ankyrin-like repeats. The protein is localized to the nucleus, functioning as a transcriptional regulator. Expression of this protein is induced during recovery following starvation.[6]

Interactions

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ANKRD23 has been shown to interact with Titin[7] and MYPN.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163126Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000067653Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ikeda K, Emoto N, Matsuo M, Yokoyama M (Feb 2003). "Molecular identification and characterization of a novel nuclear protein whose expression is up-regulated in insulin-resistant animals". J Biol Chem. 278 (6): 3514–20. doi:10.1074/jbc.M204563200. PMID 12456686.
  6. ^ a b "Entrez Gene: ANKRD23 ankyrin repeat domain 23".
  7. ^ a b Miller, Melanie K; Bang Marie-Louise; Witt Christian C; Labeit Dietmar; Trombitas Charles; Watanabe Kaori; Granzier Henk; McElhinny Abigail S; Gregorio Carol C; Labeit Siegfried (Nov 2003). "The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules". J. Mol. Biol. 333 (5): 951–64. doi:10.1016/j.jmb.2003.09.012. ISSN 0022-2836. PMID 14583192.
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Further reading

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