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Amelogenin, Y isoform is a protein that in humans is encoded by the AMELY (amelogenin, Y-linked) gene.[5][6]

AMELY
Identifiers
AliasesAMELY, AMGL, AMGY, amelogenin, Y-linked, amelogenin Y-linked
External IDsOMIM: 410000 MGI: 88005 HomoloGene: 47996 GeneCards: AMELY
Gene location (Human)
Y chromosome (human)
Chr.Y chromosome (human)[1]
Y chromosome (human)
Genomic location for AMELY
Genomic location for AMELY
BandYp11.2Start6,865,918 bp[1]
End6,911,774 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001143
NM_001364814

NM_001081978
NM_009666
NM_001290371

RefSeq (protein)

NP_001134
NP_001351743

NP_001075447
NP_001277300
NP_033796

Location (UCSC)Chr Y: 6.87 – 6.91 MbChr X: 169.18 – 169.19 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

AMELY is a gene which encodes a form of amelogenin found on the Y chromosome. Amelogenin is a member of a family of extracellular matrix proteins. They are involved in biomineralization during tooth enamel development. Mutations in the related AMELX gene on the X chromosome cause X-linked amelogenesis imperfecta.[6]

ReferencesEdit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000099721 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031354 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Nakahori Y, Takenaka O, Nakagome Y (February 1991). "A human X-Y homologous region encodes "amelogenin"". Genomics. 9 (2): 264–9. doi:10.1016/0888-7543(91)90251-9. PMID 2004775.
  6. ^ a b "Entrez Gene: amelogenin".

External linksEdit

Further readingEdit