5''-phosphoribostamycin phosphatase

5′′-phosphoribostamycin phosphatase (EC 3.1.3.88) is an enzyme with systematic name 5′′-phosphoribostamycin phosphohydrolase.[1] This enzyme catalyses the following chemical reaction

5′′-phosphoribostamycin phosphatase
Identifiers
EC no.3.1.3.88
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
5′′-phosphoribostamycin + H2O ribostamycin + phosphate

This enzyme is involved in the biosynthesis of several aminocyclitol antibiotics, including ribostamycin, neomycin and butirosin.

References

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  1. ^ Kudo F, Fujii T, Kinoshita S, Eguchi T (July 2007). "Unique O-ribosylation in the biosynthesis of butirosin". Bioorganic & Medicinal Chemistry. 15 (13): 4360–8. doi:10.1016/j.bmc.2007.04.040. PMID 17482823.
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