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3-hydroxyacyl-CoA dehydratase 2

3-hydroxyacyl-CoA dehydratase 2 is a protein that in humans is encoded by the HACD2 gene. [5]

HACD2
Identifiers
AliasesHACD2, PTPLB, 3-hydroxyacyl-CoA dehydratase 2
External IDsMGI: 1918007 HomoloGene: 23409 GeneCards: HACD2
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for HACD2
Genomic location for HACD2
Band3q21.1Start123,490,820 bp[1]
End123,585,185 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001329783
NM_001329784
NM_001329786
NM_001329787
NM_198402

NM_023587

RefSeq (protein)

NP_001316712
NP_001316713
NP_001316715
NP_001316716
NP_940684

NP_076076

Location (UCSC)Chr 3: 123.49 – 123.59 MbChr 16: 35.02 – 35.11 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

FunctionEdit

The protein encoded by this gene can catalyze the third step (dehydration) in the conversion of long chain fatty acids to very long chain fatty acids. The encoded protein localizes to the endoplasmic reticulum membrane.

ReferencesEdit

Further readingEdit

This article incorporates text from the United States National Library of Medicine, which is in the public domain.