Tour de Romandie is part of the UCI World Tour, which meant that the 17 UCI WorldTeams were automatically invited and obliged to send a team. The race organisers also invited one UCI Professional Continental wildcard team to make a peloton of 18 teams. Each team entered eight riders (the maximum permitted), so 144 riders started the first stage.
The race includes six stages over six days. The first stage is a 19.2-kilometre (11.9 mi) team time trial; this is a change from recent editions of the Tour de Romandie, which have started with a prologue individual time trial. The team time trial is important both for its role in the general classification and also because the teams are using it as preparation for a similar stage in the 2015 Tour de France. Stages 2, 3 and 4 are all hilly but are expected to end in sprints. The final two stages are expected to be the decisive ones in the general classification: the fifth stage includes several climbs and a summit finish at Champex-Lac and the sixth stage is a 17.3-kilometre (10.7 mi) individual time trial around Lausanne.
The first stage of the race was a 19.2-kilometre (11.9 mi) team time trial. In this event, each team sets off together; the team's time is that of the fifth rider across the finish line. The riders who arrive at the same time as the fifth rider or before him are credited with the team's time; riders who arrive after the fifth rider are credited with their actual arrival time. The teams set off at five-minute intervals: Team Europcar set off first at 15:45 and Team Sky set off last at 17:10. The start line was at the south-western end of the Lac de Joux in Le Sentier; the riders first headed south-west for about 2.5 kilometres (1.6 mi), then turned north-east. The course went through L'Orient, then continued along the southern coast of the lake through L'Abbaye and Le Pont at the northern end of the lake. The course to this point had been generally flat, but the last 3 kilometres (1.9 mi) of the course included the climb of the Col du Mont d'Orzeires and the descent to the finish line in the Juraparc.
As they set off first, Europcar set the first benchmark time of 22' 26" at an average speed of 51.4 km/h (31.9 mph). LottoNL–Jumbo, the next team to set off, moved ahead of them by 12 seconds; this time was immediately beaten by Cannondale–Garmin who set a time of 21' 59" at an average speed of 52.4 km/h (32.6 mph). Cannondale–Garmin's lead lasted some time as the next six teams to set off were all slower. After half of the eighteen teams had finished, they held a one-second lead over Lampre–Merida. The tenth team to set off was Orica–GreenEDGE, who set a time 40 seconds faster than Cannondale–Garmin. The team had five riders together (the minimum permitted) as they crossed the line, with the Swiss Michael Albasini crossing the line first.
The final teams to set off included the world champions in the team time trial, BMC Racing Team, and the former world champions, Etixx–Quick-Step. None of the next seven teams were able to beat Orica–GreenEDGE's time and, with one team left to finish, they still led by 5 seconds ahead of Team Katusha. The final team to set off was Team Sky; they set an identical time at the intermediate checkpoint; at the end of the stage Sky won by 0.6 seconds. Geraint Thomas was the first rider across the line and so was the first leader of the race; he had previously worn the yellow jersey in the 2012 Tour de Romandie.Luke Rowe was the best young rider after the first stage, while 11 riders shared the same time as Thomas.
In the 2015 Tour de Romandie, four jerseys were awarded. The general classification was calculated by adding up each cyclist's finishing times on each stage. Time bonuses were awarded to the first three finishers on road stages (stages 2–5): the stage winner won a ten-second bonus, with six and four seconds for the second and third riders respectively. No bonus seconds were awarded at intermediate sprints. The leader of the general classification received a yellow jersey. This classification was considered the most important of the Tour, and the winner of the classification was considered the winner of the race. The young rider classification was based on the general classification: the highest-ranked rider born after 1 January 1990 was the leader of the classification and wore a white jersey.
There was a mountains classification; the leader of this competition wore a pink jersey. Over the road stages of the race, there were 15 classified climbs, each of which was ranked as first-category, second-category or third-category. The first riders to cross the summit of the climbs won points towards the mountain classification. On first-category climbs, the first five riders won points with the first of these winning 12 points. Points were also awarded to the first five riders across the summit of second-category climbs, though the winner only won 8 points. On third-category climbs, only the first four riders won points, with the first rider winning five points. There was also a points classification. On each of the road stages, there were two intermediate sprints. The first rider in these sprints won 6 points; the second rider won 3 points; the third rider won 1 point. No points were awarded at stage finishes. The winner of the classification won a green jersey.
The final individual classification was a combativity prize. After each road stage, a jury chose the rider on the basis of sportsmanship and effort in the stage. The rider was awarded a red dossard (race number) for the following stage. After the final stage, the jury chose the most combative rider of the race overall.
The final classification was a team classification. This was calculated by adding together the times of the best three riders on each team in each stage except the team time trial. In this stage, the team's finishing time was that of the fifth rider across the line.