Three-time defending champion Esther Vergeer defeated Sharon Walraven in the final, 6–0, 6–0 to win the women's singles wheelchair tennis title at the 2010 French Open. Vergeer lost no sets and only four games en route to the title.
| Wheelchair women's singles | |
|---|---|
| 2010 French Open | |
| Champion |  Esther Vergeer |
| Runner-up | Sharon Walraven |
| Score | 6–0, 6–0 |
Seeds edit
Esther Vergeer (champion)
Florence Gravellier (semifinals)
Draw edit
Key edit
- Q = Qualifier
- WC = Wild card
- LL = Lucky loser
- Alt = Alternate
- SE = Special exempt
- PR = Protected ranking
- ITF = ITF entry
- JE = Junior exempt
- w/o = Walkover
- r = Retired
- d = Defaulted
- SR = Special ranking
Finals edit
| Quarterfinals | Semifinals | Final | ||||||||||||||||||
| 1 | Esther Vergeer
| 6 | 6 | |||||||||||||||||
| Jiske Griffioen
| 2 | 1 | ||||||||||||||||||
| 1 | Esther Vergeer
| 6 | 6 | |||||||||||||||||
 Daniela Di Toro
| 0 | 1 | ||||||||||||||||||
| Aniek van Koot
| 6 | 0 | 63 | |||||||||||||||||
| Daniela Di Toro
| 4 | 6 | 77 | |||||||||||||||||
| 1 | Esther Vergeer
| 6 | 6 | |||||||||||||||||
| Sharon Walraven
| 0 | 0 | ||||||||||||||||||
 Ju Yeon Park
| 2 | 4 | ||||||||||||||||||
| Sharon Walraven
| 6 | 6 | ||||||||||||||||||
| Sharon Walraven
| 6 | 7 | ||||||||||||||||||
| 2 |  Florence Gravellier
| 4 | 5 | |||||||||||||||||
 Katharina Krüger
| 0 | 1 | ||||||||||||||||||
| 2 | Florence Gravellier
| 6 | 6 | |||||||||||||||||