The enzyme (R)-limonene synthase (EC 4.2.3.20) catalyzes the reversible chemical reaction
- geranyl diphosphate (+)-(4R)-limonene + diphosphate.
| (R)-limonene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.20 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Description edit
This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is Geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-(4R)-limonene-forming]. Other names in common use include Limonene synthase, and Geranyldiphosphate diphosphate lyase [(+)-(R)-limonene-forming].
The enzyme participates in monoterpenoid biosynthesis and is localized to Leucoplasts of oil gland secretory cells.[1]
References edit
- ^ Turner G, Gershenzon J, Nielson EE, Froehlich JE, Croteau R (July 1999). "Limonene synthase, the enzyme responsible for monoterpene biosynthesis in peppermint, is localized to leucoplasts of oil gland secretory cells". Plant Physiology. 120 (3): 879–86. doi:10.1104/pp.120.3.879. PMC 59327. PMID 10398724.
Further reading edit
This article includes a list of general references, but it lacks sufficient corresponding inline citations. (March 2020) |
- Bouwmeester HJ, Gershenzon J, Konings MC, Croteau R (July 1998). "Biosynthesis of the monoterpenes limonene and carvone in the fruit of caraway. I. Demonstration Of enzyme activities and their changes with development". Plant Physiology. 117 (3): 901–12. doi:10.1104/pp.117.3.901. PMC 34944. PMID 9662532.
- Lücker J, El Tamer MK, Schwab W, Verstappen FW, van der Plas LH, Bouwmeester HJ, Verhoeven HA (July 2002). "Monoterpene biosynthesis in lemon (Citrus limon). cDNA isolation and functional analysis of four monoterpene synthases". European Journal of Biochemistry. 269 (13): 3160–71. doi:10.1046/j.1432-1033.2002.02985.x. PMID 12084056.
