(4S)-beta-phellandrene synthase (geranyl-diphosphate-cyclizing)

β-Phellandrene synthase (EC 4.2.3.52, geranyl-diphosphate-cyclizing) (phellandrene synthase, (−)-β-phellandrene synthase, (−)-(4S)-β-phellandrene synthase) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase (cyclizing; β-phellandrene-forming).[1][2][3][4] This enzyme catalyses the following chemical reaction

β-phellandrene synthase (geranyl-diphosphate-cyclizing)
Identifiers
EC no.4.2.3.52
CAS no.137010-34-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
geranyl diphosphate β-phellandrene + diphosphate

This enzyme requires ion Mn2+.

References

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  1. ^ Savage TJ, Hatch MW, Croteau R (February 1994). "Monoterpene synthases of Pinus contorta and related conifers. A new class of terpenoid cyclase". The Journal of Biological Chemistry. 269 (6): 4012–20. PMID 8307957.
  2. ^ Bohlmann J, Phillips M, Ramachandiran V, Katoh S, Croteau R (August 1999). "cDNA cloning, characterization, and functional expression of four new monoterpene synthase members of the Tpsd gene family from grand fir (Abies grandis)". Archives of Biochemistry and Biophysics. 368 (2): 232–43. doi:10.1006/abbi.1999.1332. PMID 10441373.
  3. ^ Wagschal K, Savage TJ, Croteau R (1991). "Isotopically sensitive branching as a tool for evaluating multiple product formation by monoterpene cyclases". Tetrahedron. 31: 5933–5944. doi:10.1016/s0040-4020(01)86486-3.
  4. ^ LaFever RE, Croteau R (March 1993). "Hydride shifts in the biosynthesis of the p-menthane monoterpenes alpha-terpinene, gamma-terpinene, and beta-phellandrene". Archives of Biochemistry and Biophysics. 301 (2): 361–6. doi:10.1006/abbi.1993.1156. PMID 8460944.
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