(−)-gamma-cadinene synthase ((2Z,6E)-farnesyl diphosphate cyclizing)

(−)-γ-Cadinene synthase (EC 4.2.3.62, (2Z,6E)-farnesyl diphosphate cyclizing) ((−)-γ-cadinene cyclase) is an enzyme with the systematic name (2Z,6E)-farnesyl-diphosphate diphosphate-lyase ((−)-γ-cadinene-forming).[1] This enzyme catalyses the following chemical reaction:

(−)-γ-cadinene synthase ((2Z,6E)-farnesyl diphosphate cyclizing)
Identifiers
EC no.4.2.3.62
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins
(2Z,6E)-farnesyl diphosphate (−)-γ-cadinene + [diphosphate]

This enzyme is isolated from the liverwort Heteroscyphus planus.

References

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  1. ^ Nabeta K, Fujita M, Komuro K, Katayama K, Takasawa T (1997). "In vitro biosynthesis of cadinanes by cell-free extracts of cultured cells of Heteroscyphus planus". J. Chem. Soc., Perkin Trans. 1 (14): 2065–2070. doi:10.1039/a701145h.
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