G antigen family D member 2 is a protein that in humans is encoded by the XAGE1D gene.[3]

XAGE1B
Identifiers
AliasesXAGE1B, CT12.1, CT12.1C, CT12.1D, CT12.1E, CTP9, GAGED2, XAGE-1, XAGE1, XAGE1C, XAGE1D, X antigen family member 1E, X antigen family member 1B, XAGE1E, CT12.1b
External IDsOMIM: 300289, 300744, 300745; HomoloGene: 135786; GeneCards: XAGE1B; OMA:XAGE1B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

RefSeq (protein)

NP_001091073
NP_001091074
NP_065144

n/a

Location (UCSC)Chr X: 52.51 – 52.52 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene generates 3 transcript variants, and one of which includes 2 transcripts generated from alternate transcription initiation sites.[3]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000204382Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b "Entrez Gene: XAGE1 X antigen family, member 1".

Further reading

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