William Sharkey may refer to:
- William L. Sharkey (1798–1873), American judge and politician
- William J. Sharkey (US Navy officer) (1885–1918), officer in the United States Navy during World War I
- William J. Sharkey (murderer) (1847–?), convicted murderer and minor New York City politician
This disambiguation page lists articles about people with the same name.
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